8U9I

Pasteurella multocida alpha2,3/2,6 sialyltransferase D141N bound to CMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alpha-2,3/2,6-sialyltransferase/sialidase	polymer	399	46466.5	2	UniProt (Q15KI8) Pfam (PF11477) UniProt (by SIFTS) (Q9CP67)	Pasteurella multocida
2	C (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS) PubChem (3777159)
3	D, F (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG) PubChem (8117)
4	E, G (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
5	H, I (A, B)	water	water		18.0	940	Chemie (HOH)

Sequence modifications

A, B: 26 - 412 (UniProt: Q15KI8)

PDB	External Database	Details
Met 25	-	initiating methionine
Asn 141	Asp 141	engineered mutation
Gly 413	-	expression tag
Gly 414	-	expression tag
Gly 415	-	expression tag
Leu 416	-	expression tag
Glu 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92933.0
Non-Polymers*	Number of molecules	5
	Total formula weight	518.6
All*	Total formula weight	93451.5

*Water molecules are not included.