8U92
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | N-acetylneuraminate lyase | polymer | 305 | 33738.6 | 6 | UniProt (A0A0H3FJT8) Pfam (PF00701) | Klebsiella aerogenes KCTC 2190 | |
| 2 | FA, G, GA, H, N... (D, A, B, E, C...) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 12 | Chemie (MPD) | |||
| 3 | HA, I, P, QA, W... (D, A, B, E, C...) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 4 | AA, AB, BA, BB, CB... (C, F, D, A, B...) | CHLORIDE ION | non-polymer | 35.5 | 28 | Chemie (CL) | |||
| 5 | CA, DA, EA, M, NA... (C, A, D, B, E) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | HB, IB, JB, KB, LB... (A, B, C, D, E...) | water | water | 18.0 | 943 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 297 (UniProt: A0A0H3FJT8)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 93 | Val 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 202431.4 | |
| Non-Polymers* | Number of molecules | 53 |
| Total formula weight | 3193.4 | |
| All* | Total formula weight | 205624.8 |
