8U8W
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-acetylneuraminate lyase | polymer | 305 | 33669.5 | 1 | UniProt (A0A0H3FJT8) Pfam (PF00701) | Klebsiella aerogenes KCTC 2190 | |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E, F (A) | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 5 | G (A) | PYRUVIC ACID | non-polymer | 88.1 | 1 | Chemie (PYR) | |||
| 6 | H, I, J, K (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | L (A) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A: 1 - 297 (UniProt: A0A0H3FJT8)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 93 | Val 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33669.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 804.1 | |
| All* | Total formula weight | 34473.7 |
