8U57

PPARg LBD in complex with perfluorooctanoic acid (PFOA)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Peroxisome proliferator-activated receptor gamma	polymer	290	33316.5	1	UniProt (P37231) In PDB	Homo sapiens (human)
2	A	pentadecafluorooctanoic acid	non-polymer		414.1	4	Chemie (8PF)
3	A	(4S,5S)-1,2-DITHIANE-4,5-DIOL	non-polymer		152.2	1	Chemie (D1D)
4		water	water		18.0	112	Chemie (HOH)

Sequence modifications

A: 203 - 477 (UniProt: P37231)

PDB	External Database	Details
Met 188	-	initiating methionine
Ala 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
Val 196	-	expression tag
Asp 197	-	expression tag
Asp 198	-	expression tag
Asp 199	-	expression tag
Asp 200	-	expression tag
Lys 201	-	expression tag
Met 202	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33316.5
Non-Polymers*	Number of molecules	5
	Total formula weight	1808.5
All*	Total formula weight	35125.0

*Water molecules are not included.