8U57
PPARg LBD in complex with perfluorooctanoic acid (PFOA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 290 | 33316.5 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | |
| 2 | B, C, D, F (A) | pentadecafluorooctanoic acid | non-polymer | 414.1 | 4 | Chemie (8PF) | |||
| 3 | E (A) | (4S,5S)-1,2-DITHIANE-4,5-DIOL | non-polymer | 152.2 | 1 | Chemie (D1D) | |||
| 4 | G (A) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Met 188 | - | initiating methionine |
| Ala 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| His 193 | - | expression tag |
| His 194 | - | expression tag |
| His 195 | - | expression tag |
| Val 196 | - | expression tag |
| Asp 197 | - | expression tag |
| Asp 198 | - | expression tag |
| Asp 199 | - | expression tag |
| Asp 200 | - | expression tag |
| Lys 201 | - | expression tag |
| Met 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33316.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1808.5 | |
| All* | Total formula weight | 35125.0 |
