8U56

The mTORC1 cholesterol sensor LYCHOS (GPR155)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Integral membrane protein GPR155	polymer	890	99276.9	2	UniProt (Q7Z3F1) Pfam (PF03547) Pfam (PF00610)	Homo sapiens (human)
2	C, E (A, B)	Lauryl Maltose Neopentyl Glycol	non-polymer		1005.2	2	Chemie (LMN)
3	D, F (A, B)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	2	Chemie (Y01)

Sequence modifications

A, B: 1 - 870 (UniProt: Q7Z3F1)

PDB	External Database	Details
Gly 871	-	expression tag
Ser 872	-	expression tag
Gly 873	-	expression tag
Ser 874	-	expression tag
Asp 875	-	expression tag
Tyr 876	-	expression tag
Lys 877	-	expression tag
Asp 878	-	expression tag
Asp 879	-	expression tag
Asp 880	-	expression tag
Asp 881	-	expression tag
Lys 882	-	expression tag
Asp 883	-	expression tag
Tyr 884	-	expression tag
Lys 885	-	expression tag
Asp 886	-	expression tag
Asp 887	-	expression tag
Asp 888	-	expression tag
Asp 889	-	expression tag
Lys 890	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	198553.8
Non-Polymers*	Number of molecules	4
	Total formula weight	2983.8
All*	Total formula weight	201537.6

*Water molecules are not included.