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8U4E

Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Insulin receptorpolymer1382156518.32UniProt (P06213)
Pfam (PF01030)
Pfam (PF00757)
Pfam (PF00041)
Pfam (PF17870)
Pfam (PF07714)
Homo sapiens (human)
2C, D, E
(C, D, E)
Insulin-like growth factor IIpolymer18020170.43UniProt (P01344)
Pfam (PF00049)
Pfam (PF08365)
Homo sapiens (human)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight373547.9
All*Total formula weight373547.9
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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