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8U4C

Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Insulin receptorpolymer1382156518.32UniProt (P06213)
Pfam (PF01030)
Pfam (PF00757)
Pfam (PF00041)
Pfam (PF17870)
Pfam (PF07714)
Homo sapiens (human)
2C, D, E, F
(C, D, E, F)
Insulin-like growth factor IIpolymer18020170.44UniProt (P01344)
Pfam (PF00049)
Pfam (PF08365)
Homo sapiens (human)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight393718.2
All*Total formula weight393718.2
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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