8U31
Crystal structure of PD-1 in complex with a Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Programmed cell death protein 1 | polymer | 140 | 15765.3 | 1 | UniProt (Q15116) Pfam (PF07686) In PDB | Homo sapiens (human) | |
2 | B | Fab light chain | polymer | 218 | 23509.8 | 1 | Homo sapiens (human) | ||
3 | C | Fab heavy chain | polymer | 229 | 24031.0 | 1 | Homo sapiens (human) | ||
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A: 25 - 146 (UniProt: Q15116)
PDB | External Database | Details |
---|---|---|
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
Gly 16 | - | expression tag |
Glu 17 | - | expression tag |
Asn 18 | - | expression tag |
Leu 19 | - | expression tag |
Tyr 20 | - | expression tag |
Phe 21 | - | expression tag |
Gln 22 | - | expression tag |
Gly 23 | - | expression tag |
Ser 24 | - | expression tag |
Ser 93 | Cys 93 | conflict |
Gly 147 | - | expression tag |
Asn 148 | - | expression tag |
Ser 149 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 63306.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 63398.2 |