8U31
Crystal structure of PD-1 in complex with a Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death protein 1 | polymer | 140 | 15765.3 | 1 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (human) | |
| 2 | B (B) | Fab light chain | polymer | 218 | 23509.8 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Fab heavy chain | polymer | 229 | 24031.0 | 1 | Homo sapiens (human) | ||
| 4 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | E, F (B, C) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A: 25 - 146 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| Gly 16 | - | expression tag |
| Glu 17 | - | expression tag |
| Asn 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Tyr 20 | - | expression tag |
| Phe 21 | - | expression tag |
| Gln 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Ser 93 | Cys 93 | conflict |
| Gly 147 | - | expression tag |
| Asn 148 | - | expression tag |
| Ser 149 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63306.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 63398.2 |
