8U2P

Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glycine--tRNA ligase	polymer	476	54475.2	1	UniProt (P9WFV7) Pfam (PF00587) Pfam (PF03129)	Mycobacterium tuberculosis	Glycyl-tRNA synthetase,GlyRS
2	B (A)	5'-O-(glycylsulfamoyl)adenosine	non-polymer		403.4	1	Chemie (G5A)
3	C, D (A)	IMIDAZOLE	non-polymer		69.1	2	Chemie (IMD)
4	E (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
5	F, G, H (A)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	I (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7	J, K (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
8	L (A)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A: -3 - 461 (UniProt: P9WFV7)

PDB	External Database	Details
Met -16	-	initiating methionine
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
Gly -7	-	expression tag
Gly -6	-	expression tag
Gly -5	-	expression tag
Gly -4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54475.2
Non-Polymers*	Number of molecules	10
	Total formula weight	1018.2
All*	Total formula weight	55493.4

*Water molecules are not included.