8U1E

Apo protein tyrosine phosphatase 1B (PTP1B) at high resolution (1.43 A) in space group P43212 with two distinctly ordered chains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein phosphatase non-receptor type 1	polymer	330	38568.0	2	UniProt (P18031) Pfam (PF00102) In PDB	Homo sapiens (human)
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3		water	water		18.0	389	Chemie (HOH)

Sequence modifications

A, B: 1 - 321 (UniProt: P18031)

PDB	External Database	Details
Met 0	-	initiating methionine
Leu 322	-	expression tag
Glu 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77135.9
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	77184.6

*Water molecules are not included.