Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8TZE

Structure of C-terminal half of LRRK2 bound to GZD-824

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leucine-rich repeat serine/threonine-protein kinase 2polymer2527286462.81UniProt (Q5S007)
Pfam (PF13855)
Pfam (PF08477)
Pfam (PF16095)
Pfam (PF00069)
Homo sapiens (human)
2B
(A)
4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamidenon-polymer532.61Chemie (T3X)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight286462.8
Non-Polymers*Number of molecules1
Total formula weight532.6
All*Total formula weight286995.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

PDB statisticsPDBj update infoContact PDBjnumon