8TZ2

Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, C, B)	Sodium/nucleoside cotransporter	polymer	715	79376.8	3	UniProt (F1MGR1) Pfam (PF01773) Pfam (PF07670) Pfam (PF07662)	Bos taurus (cattle)
2	D, E, H, I, L... (A, C, B)	SODIUM ION	non-polymer		23.0	6	Chemie (NA)
3	F, G, J, K, N... (A, C, B)	1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine	non-polymer		760.1	6	Chemie (LBN)
4	P, Q, R (A, C, B)	water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, C, B: 1 - 697 (UniProt: F1MGR1)

PDB	External Database	Details
Met -14	-	initiating methionine
Asp -13	-	expression tag
Tyr -12	-	expression tag
Lys -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Lys -6	-	expression tag
Leu -5	-	expression tag
Glu -4	-	expression tag
Ala -3	-	expression tag
Thr -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Ser 698	-	expression tag
Asn 699	-	expression tag
Ser 700	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	238130.3
Non-Polymers*	Number of molecules	12
	Total formula weight	4698.4
All*	Total formula weight	242828.7

*Water molecules are not included.