8TZ1
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, B | Sodium/nucleoside cotransporter | polymer | 715 | 79376.8 | 3 | UniProt (F1MGR1) Pfam (PF01773) Pfam (PF07670) Pfam (PF07662) In PDB | Bos taurus (cattle) | |
2 | A, C, B | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide | non-polymer | 244.2 | 3 | Chemie (RBV) | |||
3 | A, C, B | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
4 | A, C, B | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 12 | Chemie (LBN) | |||
5 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, C, B: 1 - 697 (UniProt: F1MGR1)
PDB | External Database | Details |
---|---|---|
Met -14 | - | initiating methionine |
Asp -13 | - | expression tag |
Tyr -12 | - | expression tag |
Lys -11 | - | expression tag |
Asp -10 | - | expression tag |
Asp -9 | - | expression tag |
Asp -8 | - | expression tag |
Asp -7 | - | expression tag |
Lys -6 | - | expression tag |
Leu -5 | - | expression tag |
Glu -4 | - | expression tag |
Ala -3 | - | expression tag |
Thr -2 | - | expression tag |
Met -1 | - | expression tag |
Ala 0 | - | expression tag |
Ser 698 | - | expression tag |
Asn 699 | - | expression tag |
Ser 700 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 238130.3 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 9991.5 | |
All* | Total formula weight | 248121.8 |