8TXT

Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin	polymer	334	37948.0	3	UniProt (Q5EP31) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33)	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
2	B, D, F (B, D, F)	Hemagglutinin	polymer	177	20414.5	3	UniProt (A0A6B7HQ27) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33)	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
3	G, I, K (H, G, J)	GC_W13B_B, Fab heavy chain	polymer	225	23641.9	3		Homo sapiens (human)
4	H, J, L (L, I, K)	GC_w13_B, Fab light chain	polymer	214	23345.8	3		Homo sapiens (human)
5	M, Q (M, Q)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
6	N, O, P, R (N, O, P, R)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
7	S, T, U, V, W... (A, C, E, F, L...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)

Sequence modifications

A, C, E: 11 - 333 (UniProt: Q5EP31)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

B, D, F: 1 - 174 (UniProt: A0A6B7HQ27)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	316050.7
Branched	Number of molecules	6
	Total formula weight	2870.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1548.5
All*	Total formula weight	320469.8

*Water molecules are not included.