8TX0
IRAK4 in complex with compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34657.9 | 2 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | C, F (A, B) | ~{N}-(1-cyclopropyl-2-oxidanylidene-pyridin-3-yl)-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-7-propan-2-yloxy-imidazo[1,2-a]pyrimidine-6-carboxamide | non-polymer | 449.5 | 2 | Chemie (VEU) | |||
| 3 | D, E, G, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | I (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69315.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1170.3 | |
| All* | Total formula weight | 70486.1 |
