8TVM
IRAK4 in complex with compound 24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34657.9 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) In PDB | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | A, B, C, D | N-{1-[(1R,2R)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1R,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide | non-polymer | 467.5 | 4 | Chemie (VDC) | |||
| 3 | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138631.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1870.0 | |
| All* | Total formula weight | 140501.7 |
