8TUG
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1733 | 191821.6 | 1 | UniProt (P04050) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB | Saccharomyces cerevisiae (baker's yeast) | RNA polymerase II subunit 1,RNA polymerase II subunit B1,DNA-directed RNA polymerase III largest subunit,RNA polymerase II subunit B220 |
| 2 | B | DNA-directed RNA polymerase subunit beta | polymer | 1224 | 138937.3 | 1 | UniProt (A0A6A5Q4H2) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (P08518) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 3 | C | DNA-directed RNA polymerase II subunit RPB3 | polymer | 318 | 35330.5 | 1 | UniProt (A0A6A5Q0Z3) Pfam (PF01193) Pfam (PF01000) UniProt (by SIFTS) (P16370) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 4 | D | DNA-directed RNA polymerase II subunit RPB4 | polymer | 221 | 25451.2 | 1 | UniProt (A0A6A5PTI6) Pfam (PF03874) UniProt (by SIFTS) (P20433) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 5 | E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | polymer | 215 | 25117.1 | 1 | UniProt (A0A6A5Q456) Pfam (PF03871) Pfam (PF01191) UniProt (by SIFTS) (P20434) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 6 | F | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 7 | G | DNA-directed RNA polymerase II subunit RPB7 | polymer | 171 | 19081.1 | 1 | UniProt (A0A6A5Q270) Pfam (PF03876) Pfam (PF00575) UniProt (by SIFTS) (P34087) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 8 | H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 146 | 16525.4 | 1 | UniProt (A0A6A5Q8C2) Pfam (PF03870) UniProt (by SIFTS) (P20436) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 9 | I | DNA-directed RNA polymerase II subunit RPB9 | polymer | 122 | 14308.2 | 1 | UniProt (A0A7I9EWC2) Pfam (PF02150) Pfam (PF01096) UniProt (by SIFTS) (P27999) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 10 | J | DNA-directed RNA polymerases II subunit RPABC5 | polymer | 70 | 8290.7 | 1 | UniProt (A0A6A5Q7Q6) Pfam (PF01194) UniProt (by SIFTS) (P22139) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 11 | K | DNA-directed RNA polymerase II subunit RPB11 | polymer | 120 | 13633.5 | 1 | UniProt (A0A6A5Q7A1) Pfam (PF13656) UniProt (by SIFTS) (P38902) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 12 | L | DNA-directed RNA polymerases II subunit RPABC4 | polymer | 70 | 7730.0 | 1 | UniProt (A0A6A5PY05) Pfam (PF03604) UniProt (by SIFTS) (P40422) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
| 13 | M | DNA repair and recombination protein RAD26 | polymer | 503 | 42825.8 | 1 | Saccharomyces cerevisiae | ||
| 14 | N | DNA (NTS) | polymer | 47 | 14494.3 | 1 | synthetic construct | ||
| 15 | T | DNA (TS) | polymer | 46 | 14275.1 | 1 | synthetic construct | ||
| 16 | R | RNA | polymer | 10 | 3264.0 | 1 | synthetic construct | ||
| 17 | A, B, C, I, J... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 18 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 589017.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 589565.1 |
