8TTF

NorA double mutant - E222QD307N at pH 7.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Quinolone resistance protein NorA	polymer	424	46653.9	1	UniProt (Q53459) Pfam (PF07690) UniProt (by SIFTS) (P0A0J7)	Staphylococcus aureus
2	B (C)	Heavy Chain of FabDA1 Variable Domain	polymer	128	14070.6	1		Homo sapiens (human)
3	C (D)	Light Chain of FabDA1 Variable Domain	polymer	105	11209.5	1		Homo sapiens (human)

Sequence modifications

A: 1 - 388 (UniProt: Q53459)

PDB	External Database	Details
Gln 222	Glu 222	engineered mutation
Asn 307	Asp 307	engineered mutation
Glu 389	-	expression tag
Asn 390	-	expression tag
Leu 391	-	expression tag
Tyr 392	-	expression tag
Phe 393	-	expression tag
Gln 394	-	expression tag
Gly 395	-	expression tag
Lys 396	-	expression tag
Leu 397	-	expression tag
Gly 398	-	expression tag
Pro 399	-	expression tag
Glu 400	-	expression tag
Gln 401	-	expression tag
Lys 402	-	expression tag
Leu 403	-	expression tag
Ile 404	-	expression tag
Ser 405	-	expression tag
Glu 406	-	expression tag
Glu 407	-	expression tag
Asp 408	-	expression tag
Leu 409	-	expression tag
Asn 410	-	expression tag
Ser 411	-	expression tag
Ala 412	-	expression tag
Val 413	-	expression tag
Asp 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	71933.9
All*	Total formula weight	71933.9

*Water molecules are not included.