8TS3
Cryo-EM structure of human MRS2 with Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Magnesium transporter MRS2 homolog, mitochondrial, Soluble cytochrome b562 fusion protein | polymer | 486 | 55471.7 | 5 | UniProt (Q9HD23) UniProt (P0ABE7) Pfam (PF22099) Pfam (PF07361) | Homo sapiens (human) | |
| 2 | F, G, H, I, J... (A, B, C, D, E) | CALCIUM ION | non-polymer | 40.1 | 7 | Chemie (CA) |
Sequence modifications
A, B, C, D, E: 62 - 431 (UniProt: Q9HD23)
A, B, C, D, E: 432 - 536 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Met 61 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Trp 438 | Met 29 | conflict |
| Ile 533 | His 124 | conflict |
| Leu 537 | - | expression tag |
| Ser 538 | - | expression tag |
| Asn 539 | - | expression tag |
| Ser 540 | - | expression tag |
| Leu 541 | - | expression tag |
| Glu 542 | - | expression tag |
| Val 543 | - | expression tag |
| Leu 544 | - | expression tag |
| Phe 545 | - | expression tag |
| Gln 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 277358.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 280.5 | |
| All* | Total formula weight | 277639.0 |
