8TR0

Metabotropic glutamate receptor 3 class 3 bound to antagonist LY 341495

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metabotropic glutamate receptor 3	polymer	921	103161.6	2	UniProt (P31422) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Rattus norvegicus (Norway rat)
2	C, D (A, B)	2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine	non-polymer		353.4	2	Chemie (Z99)

Sequence modifications

A, B: 1 - 879 (UniProt: P31422)

PDB	External Database	Details
Ala 880	-	expression tag
Gly 881	-	expression tag
Leu 882	-	expression tag
Val 883	-	expression tag
Pro 884	-	expression tag
Arg 885	-	expression tag
Gly 886	-	expression tag
Ser 887	-	expression tag
Ala 888	-	expression tag
Ala 889	-	expression tag
Ala 890	-	expression tag
Lys 891	-	expression tag
Ser 892	-	expression tag
Ala 893	-	expression tag
Trp 894	-	expression tag
Ser 895	-	expression tag
His 896	-	expression tag
Pro 897	-	expression tag
Gln 898	-	expression tag
Phe 899	-	expression tag
Glu 900	-	expression tag
Lys 901	-	expression tag
Gly 902	-	expression tag
Gly 903	-	expression tag
Gly 904	-	expression tag
Ser 905	-	expression tag
Gly 906	-	expression tag
Gly 907	-	expression tag
Gly 908	-	expression tag
Ser 909	-	expression tag
Gly 910	-	expression tag
Gly 911	-	expression tag
Gly 912	-	expression tag
Ser 913	-	expression tag
Trp 914	-	expression tag
Ser 915	-	expression tag
His 916	-	expression tag
Pro 917	-	expression tag
Gln 918	-	expression tag
Phe 919	-	expression tag
Glu 920	-	expression tag
Lys 921	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	206323.1
Non-Polymers*	Number of molecules	2
	Total formula weight	706.7
All*	Total formula weight	207029.8

*Water molecules are not included.