8TQK
Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (D, F, H) | Heavy chain Fab rPIV3-18 | polymer | 224 | 23960.0 | 3 | UniProt (by SIFTS) (P0DOX5) | Homo sapiens (human) | |
| 2 | B, D, F (E, G, L) | Light chain Fab rPIV3-28 | polymer | 214 | 23671.3 | 3 | Homo sapiens (human) | ||
| 3 | G, H, I (A, B, C) | Fusion glycoprotein F0 | polymer | 516 | 57360.1 | 3 | UniProt (A0A059QA82) | Human respirovirus 3 |
Sequence modifications
A, B, C: 19 - 481 (UniProt: A0A059QA82)
| PDB | External Database | Details |
|---|---|---|
| Cys 162 | Gln 162 | engineered mutation |
| Cys 168 | Leu 168 | engineered mutation |
| Cys 213 | Ile 213 | engineered mutation |
| Cys 230 | Gly 230 | engineered mutation |
| Val 463 | Ala 463 | engineered mutation |
| Tyr 474 | Ile 474 | engineered mutation |
| Ser 482 | - | expression tag |
| Ala 483 | - | expression tag |
| Ile 484 | - | expression tag |
| Glu 485 | - | expression tag |
| Asp 486 | - | expression tag |
| Lys 487 | - | expression tag |
| Ile 488 | - | expression tag |
| Glu 489 | - | expression tag |
| Glu 490 | - | expression tag |
| Ile 491 | - | expression tag |
| Leu 492 | - | expression tag |
| Ser 493 | - | expression tag |
| Lys 494 | - | expression tag |
| Ile 495 | - | expression tag |
| Tyr 496 | - | expression tag |
| His 497 | - | expression tag |
| Ile 498 | - | expression tag |
| Glu 499 | - | expression tag |
| Asn 500 | - | expression tag |
| Glu 501 | - | expression tag |
| Ile 502 | - | expression tag |
| Ala 503 | - | expression tag |
| Arg 504 | - | expression tag |
| Ile 505 | - | expression tag |
| Lys 506 | - | expression tag |
| Lys 507 | - | expression tag |
| Leu 508 | - | expression tag |
| Ile 509 | - | expression tag |
| Gly 510 | - | expression tag |
| Glu 511 | - | expression tag |
| Ala 512 | - | expression tag |
| Pro 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Ser 515 | - | expression tag |
| Glu 516 | - | expression tag |
| Asn 517 | - | expression tag |
| Leu 518 | - | expression tag |
| Tyr 519 | - | expression tag |
| Phe 520 | - | expression tag |
| Gln 521 | - | expression tag |
| Gly 522 | - | expression tag |
| Gly 523 | - | expression tag |
| Ser 524 | - | expression tag |
| Gly 525 | - | expression tag |
| Ser 526 | - | expression tag |
| His 527 | - | expression tag |
| His 528 | - | expression tag |
| His 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 314974.0 | |
| All* | Total formula weight | 314974.0 |
