8TQD
NF-Kappa-B1 Bound with a Covalent Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear factor NF-kappa-B p105 subunit | polymer | 207 | 22738.2 | 1 | UniProt (P19838) Pfam (PF00554) | Homo sapiens (human) | |
| 2 | B (A) | 1-(2-bromo-4-chlorophenyl)-N-{(3S)-1-[(E)-iminomethyl]pyrrolidin-3-yl}methanesulfonamide | non-polymer | 380.7 | 1 | Chemie (JMR) | |||
| 3 | C (A) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 40 - 245 (UniProt: P19838)
| PDB | External Database | Details |
|---|---|---|
| Gly 39 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22738.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 380.7 | |
| All* | Total formula weight | 23118.8 |
