8TQ6
Crystal structure of Fab.B1.23.2 in complex with MHC-I (HLA-B*44:05)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | HLA class I histocompatibility antigen B alpha chain (HLA-B*44:05) | polymer | 274 | 31802.1 | 2 | UniProt (Q860B7) | Homo sapiens (human) | MHC-I HLA-B44*05 A-chain |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | E, J (E, P) | MHC class II antigen peptide | polymer | 9 | 1090.2 | 2 | UniProt (Q9TQB0) | synthetic construct | |
| 4 | F, H (F, H) | Fab B1.23.2 Heavy Chain | polymer | 213 | 22719.4 | 2 | Mus musculus (mouse) | ||
| 5 | G, I (G, L) | Fab B1.23.2 Light Chain | polymer | 212 | 23660.2 | 2 | Mus musculus (mouse) |
Sequence modifications
A, C: 2 - 274 (UniProt: Q860B7)
B, D: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 182302.4 | |
| All* | Total formula weight | 182302.4 |
