8TQ0
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with (R)-Lipoic Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hdac6 protein | polymer | 364 | 40285.5 | 2 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) | Danio rerio (zebrafish) | Histone Deacetylase 6 |
| 2 | C, G (A, B) | DIHYDROLIPOIC ACID | non-polymer | 208.3 | 2 | Chemie (RED) | |||
| 3 | D, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, I, J (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 440 - 798 (UniProt: A7YT55)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80571.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 703.9 | |
| All* | Total formula weight | 81274.9 |
