8TPB
Synthesis, X-Ray Crystallographic and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Non-structural protein 7 | polymer | 305 | 33697.4 | 2 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | nsp7 |
| 2 | C, D (A, B) | N-[(1R)-2-(tert-butylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-N-(4-tert-butylphenyl)-2-chloroacetamide | non-polymer | 416.0 | 2 | Chemie (JVX) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67394.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 831.9 | |
| All* | Total formula weight | 68226.7 |
