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8TOI

nhTMEM16 lipid scramblase in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+ (closed state)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BLipid scramblase nhTMEM16polymer73783294.12UniProt (C7Z7K1)
Pfam (PF20877)
Pfam (PF04547)
In PDB
Fusarium vanettenii 77-13-4
2A, BCALCIUM IONnon-polymer40.14Chemie (CA)
3B, A(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoatenon-polymer749.036Chemie (PGW)
Sequence modifications
A, B: 2 - 735 (UniProt: C7Z7K1)
PDBExternal DatabaseDetails
Gly 0-expression tag
Pro 1-expression tag
Ala 736-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight166588.1
Non-Polymers*Number of molecules40
Total formula weight27124.6
All*Total formula weight193712.7
*Water molecules are not included.

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PDB entries from 2024-07-17

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