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8TNL

CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1H, D, AH7.HK1 Neutralizing Antibody Heavy Chainpolymer11912856.23Homo sapiens (human)
2L, E, BH7.HK1 Neutralizing Antibody Heavy Chainpolymer11212153.73Homo sapiens (human)
3C, I, KHemagglutininpolymer56663075.73UniProt (A0A067Y6L0)
Pfam (PF00509)
In PDB
Influenza A virus (A/Shanghai/02/2013(H7N9))
4C, I, K2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.27Chemie (NAG)
Sequence modifications
C, I, K: -17 - 497 (UniProt: A0A067Y6L0)
PDBExternal DatabaseDetails
Cys 20Thr 38conflict
Ser 128Ala 146conflict
Val 205Ala 223conflict
Tyr 274His 292conflict
Arg 316-insertion
Arg 316-insertion
Arg 316-insertion
Arg 316-insertion
Arg 316-insertion
Cys 368Gln 386conflict
Gly 496Pro 514conflict
Ser 498-expression tag
Gly 499-expression tag
Arg 500-expression tag
Leu 501-expression tag
Val 502-expression tag
Pro 503-expression tag
Arg 504-expression tag
Gly 505-expression tag
Ser 506-expression tag
Pro 507-expression tag
Gly 508-expression tag
Ser 509-expression tag
Gly 510-expression tag
Tyr 511-expression tag
Ile 512-expression tag
Pro 513-expression tag
Glu 514-expression tag
Ala 515-expression tag
Pro 516-expression tag
Arg 517-expression tag
Asp 518-expression tag
Gly 519-expression tag
Gln 520-expression tag
Ala 521-expression tag
Tyr 522-expression tag
Val 523-expression tag
Arg 524-expression tag
Lys 525-expression tag
Asp 526-expression tag
Gly 527-expression tag
Glu 528-expression tag
Trp 529-expression tag
Val 530-expression tag
Leu 531-expression tag
Leu 532-expression tag
Ser 533-expression tag
Thr 534-expression tag
Phe 535-expression tag
Leu 536-expression tag
Gly 537-expression tag
His 538-expression tag
His 539-expression tag
His 540-expression tag
His 541-expression tag
His 542-expression tag
His 543-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight264256.9
Non-Polymers*Number of molecules7
Total formula weight1548.5
All*Total formula weight265805.3
*Water molecules are not included.

221371

PDB entries from 2024-06-19

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