8TNJ
Cryo-EM structure of HLA-B*73:01 bound to a 9mer peptide and two Fabs
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 9mer peptide,Beta-2-microglobulin,MHC class I antigen chimera | polymer | 439 | 49165.8 | 1 | UniProt (P61771) UniProt (A0A583ZBV1) In PDB | Homo sapiens | |
2 | C | B.8 Fab light chain | polymer | 216 | 23523.1 | 1 | Homo sapiens | ||
3 | D | B.8 Fab heavy chain | polymer | 232 | 24684.6 | 1 | Homo sapiens | ||
4 | E | B.1 Fab heavy chain | polymer | 238 | 25284.0 | 1 | Homo sapiens | ||
5 | F | B.1 Fab light chain | polymer | 215 | 23478.1 | 1 | Homo sapiens |
Sequence modifications
A: 25 - 123 (UniProt: P61771)
A: 145 - 423 (UniProt: A0A583ZBV1)
PDB | External Database | Details |
---|---|---|
Asn 1 | - | insertion |
Arg 2 | - | insertion |
Phe 3 | - | insertion |
Leu 4 | - | insertion |
Gly 5 | - | insertion |
Asp 6 | - | insertion |
Tyr 7 | - | insertion |
Val 8 | - | insertion |
Val 9 | - | insertion |
Gly 10 | - | linker |
Gly 11 | - | linker |
Gly 12 | - | linker |
Gly 13 | - | linker |
Ser 14 | - | linker |
Gly 15 | - | linker |
Gly 16 | - | linker |
Gly 17 | - | linker |
Gly 18 | - | linker |
Ser 19 | - | linker |
Gly 20 | - | linker |
Gly 21 | - | linker |
Gly 22 | - | linker |
Gly 23 | - | linker |
Ser 24 | - | linker |
Gly 125 | - | linker |
Gly 126 | - | linker |
Gly 127 | - | linker |
Gly 128 | - | linker |
Ser 129 | - | linker |
Gly 130 | - | linker |
Gly 131 | - | linker |
Gly 132 | - | linker |
Gly 133 | - | linker |
Ser 134 | - | linker |
Gly 135 | - | linker |
Gly 136 | - | linker |
Gly 137 | - | linker |
Gly 138 | - | linker |
Ser 139 | - | linker |
Gly 140 | - | linker |
Gly 141 | - | linker |
Gly 142 | - | linker |
Gly 143 | - | linker |
Ser 144 | - | linker |
PDB | External Database | Details |
---|---|---|
Leu 414 | Cys 294 | conflict |
Gly 421 | - | insertion |
Gly 422 | Ser 301 | conflict |
Gly 424 | - | expression tag |
Leu 425 | - | expression tag |
Glu 426 | - | expression tag |
Val 427 | - | expression tag |
Leu 428 | - | expression tag |
Phe 429 | - | expression tag |
Gln 430 | - | expression tag |
Gly 431 | - | expression tag |
Pro 432 | - | expression tag |
His 433 | - | expression tag |
His 434 | - | expression tag |
His 435 | - | expression tag |
His 436 | - | expression tag |
His 437 | - | expression tag |
His 438 | - | expression tag |
His 439 | - | expression tag |
His 440 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 146135.6 | |
All* | Total formula weight | 146135.6 |