8TNC

De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo niraparib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	De novo designed protein	polymer	147	16203.9	3		synthetic construct
2	D, E, F (A, B, C)	2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide	non-polymer		320.4	3	Chemie (3JD)
3	G, H, I (A, B, C)	water	water		18.0	269	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48611.8
Non-Polymers*	Number of molecules	3
	Total formula weight	961.2
All*	Total formula weight	49573.0

*Water molecules are not included.