8TMT
Crystal structure of KPC-44 carbapenemase in complex with vaborbactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | beta-lactamase | polymer | 282 | 30035.7 | 1 | UniProt (A0A4Y5JTU1) Pfam (PF00144) Pfam (PF13354) | Klebsiella pneumoniae | |
| 2 | B (A) | Vaborbactam | non-polymer | 297.1 | 1 | Chemie (4D6) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | F (A) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 7 | H, I (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 8 | J (A) | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 26 - 306 (UniProt: A0A4Y5JTU1)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| His 24 | - | expression tag |
| Met 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30035.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 696.3 | |
| All* | Total formula weight | 30732.1 |
