8TMR
Crystal structure of KPC-44 carbapenemase complexed with avibactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | beta-lactamase | polymer | 282 | 30035.7 | 1 | UniProt (A0A4Y5JTU1) Pfam (PF00144) Pfam (PF13354) | Klebsiella pneumoniae | |
| 2 | B (A) | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | non-polymer | 267.3 | 1 | Chemie (NXL) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | F (A) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A: 26 - 306 (UniProt: A0A4Y5JTU1)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| His 24 | - | expression tag |
| Met 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30035.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 486.4 | |
| All* | Total formula weight | 30522.1 |
