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8TM4

Human pre 13S proteasome assembly intermediate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proteasome subunit alpha type-2polymer23425927.51UniProt (P25787)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3
2B
(B)
Proteasome subunit alpha type-4polymer26129525.81UniProt (P25789)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L
3C
(C)
Proteasome subunit alpha type-7polymer24827929.91UniProt (O14818)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Proteasome subunit RC6-1,Proteasome subunit XAPC7
4D
(D)
Proteasome subunit alpha type-5polymer24126436.01UniProt (P28066)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain
5E
(E)
Proteasome subunit alpha type-1polymer26329595.61UniProt (P25786)
Pfam (PF00227)
Pfam (PF10584)
Homo sapiens (human)30 kDa prosomal protein,PROS-30,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain
6F
(F)
Proteasome subunit alpha type-3polymer25528469.31UniProt (P25788)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8
7G
(G)
Proteasome subunit alpha type-6polymer24627432.51UniProt (P60900)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)27 kDa prosomal protein,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain
8H
(H)
Proteasome subunit beta type-7polymer27730000.41UniProt (Q99436)
Pfam (PF00227)
Pfam (PF12465)
Homo sapiens (human)Macropain chain Z,Multicatalytic endopeptidase complex chain Z,Proteasome subunit Z
9I
(I)
Proteasome subunit beta type-3polymer20522972.91UniProt (P49720)
Pfam (PF00227)
Homo sapiens (human)Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain
10J
(J)
Proteasome subunit beta type-2polymer20122864.31UniProt (P49721)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,Proteasome component C7-I
11K
(c)
Proteasome assembly chaperone 1polymer28832891.91UniProt (O95456)
Pfam (PF16094)
Homo sapiens (human)PAC-1,Chromosome 21 leucine-rich protein,C21-LRP,Down syndrome critical region protein 2
12L
(d)
Proteasome assembly chaperone 2polymer26429423.01UniProt (Q969U7)
Pfam (PF09754)
Homo sapiens (human)PAC-2,Hepatocellular carcinoma-susceptibility protein 3,Tumor necrosis factor superfamily member 5-induced protein 1
13M
(e)
Proteasome maturation proteinpolymer14115805.01UniProt (Q9Y244)
Pfam (PF05348)
Homo sapiens (human)Proteassemblin,Protein UMP1 homolog,hUMP1,Voltage-gated K channel beta subunit 4.1
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight349274.1
All*Total formula weight349274.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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