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8TM3

Human proteasome alpha ring assembly intermediate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proteasome subunit alpha type-2polymer23425927.51UniProt (P25787)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3
2B
(B)
Proteasome subunit alpha type-4polymer26129525.81UniProt (P25789)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L
3C
(C)
Proteasome subunit alpha type-7polymer24827929.91UniProt (O14818)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Proteasome subunit RC6-1,Proteasome subunit XAPC7
4D
(D)
Proteasome subunit alpha type-5polymer24126436.01UniProt (P28066)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain
5E
(E)
Proteasome subunit alpha type-1polymer26329595.61UniProt (P25786)
Pfam (PF00227)
Pfam (PF10584)
Homo sapiens (human)30 kDa prosomal protein,PROS-30,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain
6F
(F)
Proteasome subunit alpha type-3polymer25528469.31UniProt (P25788)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8
7G
(G)
Proteasome subunit alpha type-6polymer24627432.51UniProt (P60900)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)27 kDa prosomal protein,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain
8H
(c)
Proteasome assembly chaperone 1polymer28832891.91UniProt (O95456)
Pfam (PF16094)
Homo sapiens (human)PAC-1,Chromosome 21 leucine-rich protein,C21-LRP,Down syndrome critical region protein 2
9I
(d)
Proteasome assembly chaperone 2polymer26429423.01UniProt (Q969U7)
Pfam (PF09754)
Homo sapiens (human)PAC-2,Hepatocellular carcinoma-susceptibility protein 3,Tumor necrosis factor superfamily member 5-induced protein 1
10J
(i)
Proteasome assembly chaperone 3polymer12213118.41UniProt (Q9BT73)
Pfam (PF10178)
Homo sapiens (human)PAC-3,hPAC3
11K
(j)
Proteasome assembly chaperone 4polymer12313789.61UniProt (Q5JS54)
Pfam (PF16093)
Homo sapiens (human)PAC-4,hPAC4
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight284539.6
All*Total formula weight284539.6
*Water molecules are not included.

247035

PDB entries from 2026-01-07

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