8TLO
Crystal Structure Analysis of BCL11A in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B-cell lymphoma/leukemia 11A | polymer | 110 | 12751.7 | 1 | UniProt (Q9H165) Pfam (PF00096) | Homo sapiens (human) | BCL-11A,B-cell CLL/lymphoma 11A,COUP-TF-interacting protein 1,Ecotropic viral integration site 9 protein homolog,EVI-9,Zinc finger protein 856 |
| 2 | B (B) | DNA (5'-D(P*CP*GP*AP*CP*CP*GP*CP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*CP*G)-3') | polymer | 19 | 5830.8 | 1 | Homo sapiens | ||
| 3 | C (C) | DNA (5'-D(P*GP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*GP*CP*GP*GP*TP*CP*GP*C)-3') | polymer | 19 | 5821.8 | 1 | Homo sapiens | ||
| 4 | D, E, F (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 730 - 835 (UniProt: Q9H165)
| PDB | External Database | Details |
|---|---|---|
| Gly 726 | - | expression tag |
| Pro 727 | - | expression tag |
| His 728 | - | expression tag |
| Met 729 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 24404.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 24600.5 |
