8TKP

Structure of the C. elegans TMC-2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Transmembrane channel-like protein 2	polymer	1203	136232.6	2	UniProt (Q11069) Pfam (PF07810)	Caenorhabditis elegans
2	B, E (B, E)	CALMyrin (Calcium and Integrin Binding protein) homolog	polymer	201	23568.6	2	UniProt (Q93640)	Caenorhabditis elegans
3	C, F (C, F)	Transmembrane inner ear expressed protein	polymer	117	12668.8	2	UniProt (Q9XXE7) Pfam (PF16038)	Caenorhabditis elegans
4	G (H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G79924RM)
5	H (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	BA, BB, HA, I, VA... (C, F, D, A)	DOCOSANE	non-polymer		310.6	6	Chemie (TWT)
7	FA, IA, J, RA, S... (C, D, A)	1,2-dioleoyl-sn-glycero-3-phosphoethanolamine	non-polymer		744.0	10	Chemie (PEE)
8	CA, CB, DA, DB, JA... (C, F, D, A)	HEXADECANE	non-polymer		226.4	22	Chemie (R16)
9	LA, M (D, A)	CHOLESTEROL	non-polymer		386.7	2	Chemie (CLR)
10	WA, X (D, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
11	AA, AB, Z, ZA (B, E)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
12	EA, EB, FB, GA (C, F)	PALMITIC ACID	non-polymer		256.4	4	Chemie (PLM)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	344940.0
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	50
	Total formula weight	16687.4
All*	Total formula weight	362476.2

*Water molecules are not included.