8TJ9

CRYSTAL STRUCTURE OF THE A/Michigan/15/2014(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hemagglutinin HA1 chain	polymer	323	35923.6	1	UniProt (A0A0Y0S9M3) Pfam (PF00509)	Influenza A virus
2	B (B)	Hemagglutinin HA2 chain	polymer	174	19996.2	1	UniProt (A0A0Y0S9M3) Pfam (PF00509)	Influenza A virus
3	C, D, E (C, D, E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
4	F (F)	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1039.9	1	In PDB GlyTouCan (G60430KO)
5	G, H, I (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	J, K, Q (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
7	L, M, T, U (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
8	N, P, R (B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
9	O (B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
10	S (B)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
11	V, W (A, B)	water	water		18.0	466	Chemie (HOH)

Sequence modifications

A: 11 - 329 (UniProt: A0A0Y0S9M3)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55919.8
Branched	Number of molecules	4
	Total formula weight	2799.6
Non-Polymers*	Number of molecules	15
	Total formula weight	1896.8
All*	Total formula weight	60616.2

*Water molecules are not included.