8TIO
Human ACKR3 with C tail extended by 12 glycines phosphorylated by GRK5 in complex with Arrestin2 reconstructed without receptor/micelle
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-arrestin-1 | polymer | 418 | 47055.5 | 1 | UniProt (P17870) Pfam (PF00339) Pfam (PF02752) UniProt (by SIFTS) (A0A4W2IM57) | Bos taurus (cattle) | Arrestin beta-1,Arrestin-2 |
| 2 | B (H) | Fab7 heavy chain | polymer | 240 | 25720.8 | 1 | synthetic construct | ||
| 3 | C (L) | Fab7 light chain | polymer | 215 | 23471.0 | 1 | Bos taurus | ||
| 4 | D (R) | Atypical chemokine receptor 3 | polymer | 405 | 46041.0 | 1 | UniProt (P25106) Pfam (PF00001) | Homo sapiens (human) | C-X-C chemokine receptor type 7,CXC-R7,CXCR-7,Chemokine orphan receptor 1,G-protein coupled receptor 159,G-protein coupled receptor RDC1 homolog,RDC-1 |
Sequence modifications
A: 1 - 418 (UniProt: P17870)
R: 4 - 376 (UniProt: P25106)
| PDB | External Database | Details |
|---|---|---|
| Ala 386 | Ile 386 | conflict |
| Ala 387 | Val 387 | conflict |
| Ala 388 | Phe 388 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Gly 337 | - | insertion |
| Gly 338 | - | insertion |
| Gly 339 | - | insertion |
| Gly 340 | - | insertion |
| Gly 341 | - | insertion |
| Gly 342 | - | insertion |
| Gly 343 | - | insertion |
| Gly 344 | - | insertion |
| Gly 345 | - | insertion |
| Gly 346 | - | insertion |
| Gly 347 | - | insertion |
| Gly 348 | - | insertion |
| Gly 377 | - | expression tag |
| Arg 378 | - | expression tag |
| Pro 379 | - | expression tag |
| Leu 380 | - | expression tag |
| Glu 381 | - | expression tag |
| Val 382 | - | expression tag |
| Leu 383 | - | expression tag |
| Phe 384 | - | expression tag |
| Gln 385 | - | expression tag |
| Gly 386 | - | expression tag |
| Pro 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| His 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| Asp 398 | - | expression tag |
| Tyr 399 | - | expression tag |
| Lys 400 | - | expression tag |
| Asp 401 | - | expression tag |
| Asp 402 | - | expression tag |
| Asp 403 | - | expression tag |
| Asp 404 | - | expression tag |
| Lys 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 142288.2 | |
| All* | Total formula weight | 142288.2 |
