8TI7

Crystal structure of profilin from Dermatophagoides pteronyssinus in complex with a poly(L-proline) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, C, E, G, I...)	Profilin	polymer	154	16948.9	8	UniProt (A0A2L0EBJ5) Pfam (PF00235)	Dermatophagoides pteronyssinus (European house dust mite)
2	I, J, K, L, M... (B, D, F, H, J...)	poly(L-proline)	polymer	12	1183.4	8		synthetic construct
3	AA, BA, Q, R, S... (O, A, G, I, K...)	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
4	CA, DA, EA, FA, GA... (A, C, E, G, I...)	water	water		18.0	161	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K, M, O: 2 - 130 (UniProt: A0A2L0EBJ5)

PDB	External Database	Details
Met -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	145058.3
Non-Polymers*	Number of molecules	12
	Total formula weight	1152.8
All*	Total formula weight	146211.1

*Water molecules are not included.