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8TI4

monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1HIgG1 Fab heavy chain, mutated to promote correct pairingpolymer22423897.71Homo sapiens
2LIgG1 Fab light chain, mutated for better pairing with cognate heavy chainpolymer21323060.71Homo sapiens
3LGLYCEROLnon-polymer92.11Chemie (GOL)
4waterwater18.0130Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46958.4
Non-Polymers*Number of molecules1
Total formula weight92.1
All*Total formula weight47050.5
*Water molecules are not included.

220472

PDB entries from 2024-05-29

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