8TI4
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | IgG1 Fab heavy chain, mutated to promote correct pairing | polymer | 224 | 23897.7 | 1 | Homo sapiens | ||
| 2 | B (L) | IgG1 Fab light chain, mutated for better pairing with cognate heavy chain | polymer | 213 | 23060.7 | 1 | Homo sapiens | ||
| 3 | C (L) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E (H, L) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46958.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 47050.5 |
