8TGV
CryoEM structure of Fab HC84.26-HCV E2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, G | envelope glycoprotein E2 | polymer | 291 | 32287.3 | 3 | UniProt (X4ZFZ7) Pfam (PF01560) In PDB | Hepacivirus C | |
2 | E, B, I, K | HC84.26 Heavy chain | polymer | 255 | 27304.6 | 4 | Homo sapiens (human) | ||
3 | F, C, J, L | HC84.26 Light chain | polymer | 234 | 25352.2 | 4 | Homo sapiens (human) | ||
4 | Z | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
5 | H, M, N | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, D, G: 384 - 645 (UniProt: X4ZFZ7)
PDB | External Database | Details |
---|---|---|
Met 363 | - | initiating methionine |
Glu 364 | - | expression tag |
Thr 365 | - | expression tag |
Asp 366 | - | expression tag |
Thr 367 | - | expression tag |
Leu 368 | - | expression tag |
Leu 369 | - | expression tag |
Leu 370 | - | expression tag |
Trp 371 | - | expression tag |
Val 372 | - | expression tag |
Leu 373 | - | expression tag |
Leu 374 | - | expression tag |
Leu 375 | - | expression tag |
Trp 376 | - | expression tag |
Val 377 | - | expression tag |
Pro 378 | - | expression tag |
Gly 379 | - | expression tag |
Ser 380 | - | expression tag |
Thr 381 | - | expression tag |
Gly 382 | - | expression tag |
Asp 383 | - | expression tag |
Ile 646 | - | expression tag |
Gly 647 | - | expression tag |
His 648 | - | expression tag |
His 649 | - | expression tag |
His 650 | - | expression tag |
His 651 | - | expression tag |
His 652 | - | expression tag |
His 653 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 307488.8 | |
Branched | Number of molecules | 4 |
Total formula weight | 1859.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 309569.8 |