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8TGP

Crystal structure of SIRT2 with FAM-PEG4-H4K16(myristoyl) peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-2polymer32336532.01UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (human)NAD-dependent protein defatty-acylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2-like protein 2
2B
(B)
H4K16(myristoyl) peptidepolymer131399.71UniProt (P62805)Homo sapiens
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(B)
MYRISTIC ACIDnon-polymer228.41Chemie (MYR)
5E, F
(A, B)
waterwater18.078Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37931.8
Non-Polymers*Number of molecules2
Total formula weight293.8
All*Total formula weight38225.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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