8TFO

Structure of MKvar

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mevalonate kinase	polymer	416	45339.8	2	UniProt (A0A1D1VW28) Pfam (PF00288) Pfam (PF08544)	Ramazzottius varieornatus
2	C, E (A, B)	(R)-MEVALONATE	non-polymer		147.1	2	Chemie (MEV)
3	D, F (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
4	G (B)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
5	H, I (A, B)	water	water		18.0	151	Chemie (HOH)

Sequence modifications

A, B: 1 - 405 (UniProt: A0A1D1VW28)

PDB	External Database	Details
Met -8	-	initiating methionine
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gly 406	-	expression tag
Ser 407	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90679.7
Non-Polymers*	Number of molecules	5
	Total formula weight	546.6
All*	Total formula weight	91226.3

*Water molecules are not included.