8TFD
Crystal structure of a stem-loop DNA aptamer complexed with SARS-CoV-2 nucleocapsid protein RNA-binding domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nucleoprotein | polymer | 130 | 14254.9 | 1 | UniProt (P0DTC9) Pfam (PF00937) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | N,Nucleocapsid protein,NC,Protein N |
| 2 | B (B) | DNA aptamer | polymer | 20 | 6165.0 | 1 | synthetic construct | ||
| 3 | C, D, E, F, G... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 46 - 174 (UniProt: P0DTC9)
| PDB | External Database | Details |
|---|---|---|
| Gly 45 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 20419.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 372.4 | |
| All* | Total formula weight | 20792.3 |
