8TF2

Wildtype rabbit TRPV5 into nanodiscs in Apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transient receptor potential cation channel subfamily V member 5	polymer	739	83784.6	4	UniProt (Q9XSM3) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520)	Oryctolagus cuniculus (rabbit)	TrpV5,Epithelial calcium channel 1,ECaC1,Osm-9-like TRP channel 3,OTRPC3
2	AA, E, F, N, O... (D, A, B, C)	ERGOSTEROL	non-polymer		396.6	8	Chemie (ERG) PubChem (16394547) PubChem (16403935) PubChem (16405182) PubChem (21139765) PubChem (21775588) PubChem (22298561) PubChem (5996) PubChem (177562045) PubChem (40469696) PubChem (40469697) PubChem (40469698) PubChem (40469699) PubChem (40826225) PubChem (40826226) PubChem (45044427) PubChem (1742286) PubChem (46936866) PubChem (53298316) PubChem (247705) PubChem (57182145) PubChem (57508500) PubChem (439550) PubChem (58992544) PubChem (59373909) PubChem (59738932) PubChem (60113883) PubChem (66824684) PubChem (444679) PubChem (69866435) PubChem (70544775) PubChem (71073084) PubChem (481705) PubChem (638020) PubChem (86575818) PubChem (69473585) PubChem (101703) PubChem (90690511) PubChem (90690567) PubChem (643780) PubChem (91171783) PubChem (91345764) PubChem (91375317) PubChem (91459231) PubChem (5317174) PubChem (5319551) PubChem (5351178) PubChem (5351845) PubChem (71122427) PubChem (5771570) PubChem (6475768) PubChem (122700025) PubChem (124099377) PubChem (124421304) PubChem (6428692) PubChem (6432563) PubChem (6433143) PubChem (6436872) PubChem (10250169) PubChem (6452576) PubChem (6713013) PubChem (6713713) PubChem (102514697) PubChem (117749797) PubChem (7067891) PubChem (7067892) PubChem (7067893) PubChem (7067894) PubChem (7094294) PubChem (121358225) PubChem (9843722) PubChem (9908757) PubChem (9930654) PubChem (9940587) PubChem (12304302) PubChem (123930382) PubChem (10982177) PubChem (11014783) PubChem (124303809) PubChem (124351226) PubChem (124427258) PubChem (124488022) PubChem (11269488) PubChem (142431933) PubChem (12304304) PubChem (12304306) PubChem (12304309) PubChem (12304314) PubChem (12304315) PubChem (124897130) PubChem (124897142) PubChem (124897144) PubChem (124897147) PubChem (124918943) PubChem (124918944) PubChem (124928616) PubChem (124928617) PubChem (125033743) PubChem (125033744) PubChem (125126218) PubChem (125126219) PubChem (163000929) PubChem (163000920) PubChem (163000938) PubChem (164664366) PubChem (126626805) PubChem (126727349) PubChem (126727350) PubChem (171157824) PubChem (129316836) PubChem (129630206) PubChem (131632336) PubChem (134279700) PubChem (142281730) PubChem (145082804) PubChem (146230523) PubChem (154496532) PubChem (161146965) PubChem (162645168) PubChem (163000919) PubChem (163000921) PubChem (163000922) PubChem (163000923) PubChem (163000924) PubChem (163000925) PubChem (163000926) PubChem (163000927) PubChem (163000928) PubChem (163000930) PubChem (163000931) PubChem (163000932) PubChem (163000933) PubChem (163000934) PubChem (163000935) PubChem (163000936) PubChem (163000937) PubChem (163000939) PubChem (163524814) PubChem (171154016) PubChem (175800618)
3	BA, G, H, I, J... (D, A, B, C)	1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		758.1	16	Chemie (CPL) PubChem (16213884) PubChem (46936342) PubChem (122218) PubChem (5287971) PubChem (6021688) PubChem (6438359) PubChem (14389437) PubChem (131706484)

Sequence modifications

A, B, C, D: 1 - 730 (UniProt: Q9XSM3)

PDB	External Database	Details
Thr 731	-	expression tag
Glu 732	-	expression tag
Thr 733	-	expression tag
Ser 734	-	expression tag
Gln 735	-	expression tag
Val 736	-	expression tag
Ala 737	-	expression tag
Pro 738	-	expression tag
Ala 739	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	335138.3
Non-Polymers*	Number of molecules	24
	Total formula weight	15302.1
All*	Total formula weight	350440.5

*Water molecules are not included.