8TEQ

Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, B, BA, C... (A, B, C, D, E...)	TRK-fused gene protein Low Complexity Domain G269V mutant	polymer	358	40490.8	30	UniProt (A0A2U3DNX3) UniProt (Q92734)	Purpureocillium lilacinum	TRK-fused gene protein, TFG

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, 0, 1, 2, 3: -5 - 230 (UniProt: A0A2U3DNX3)

PDB	External Database	Details
Met -30	-	initiating methionine
Ser -29	-	expression tag
Tyr -28	-	expression tag
Tyr -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
Asp -20	-	expression tag
Tyr -19	-	expression tag
Asp -18	-	expression tag
Ile -17	-	expression tag
Pro -16	-	expression tag
Thr -15	-	expression tag
Thr -14	-	expression tag
Glu -13	-	expression tag
Asn -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Phe -9	-	expression tag
Gln -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Ala 231	-	linker
Gly 232	-	linker
Thr 233	-	linker
Met 234	-	linker
Asp 235	-	linker
Pro 236	-	linker

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, 0, 1, 2, 3: 237 - 327 (UniProt: Q92734)

PDB	External Database	Details
Val 269	Gly 269	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	30
	Total formula weight	1214723.7
All*	Total formula weight	1214723.7

*Water molecules are not included.