8TEE

Crystal structure of Kindlin2 in complex with K794Q mutated beta1 integrin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fermitin family homolog 2	polymer	504	58094.8	2	UniProt (Q8CIB5) Pfam (PF18124) Pfam (PF00373)	Mus musculus (house mouse)	Kindlin-2,Pleckstrin homology domain-containing family C member 1
2	C, D (C, D)	Integrin beta-1	polymer	15	1622.8	2	UniProt (P09055)	Mus musculus (house mouse)	Fibronectin receptor subunit beta,VLA-4 subunit beta
3	E, F, G, H (A, B, C, D)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B: 1 - 336 (UniProt: Q8CIB5)
A, B: 513 - 680 (UniProt: Q8CIB5)
C, D: 784 - 798 (UniProt: P09055)

PDB	External Database	Details
Gln 794	Lys 794	engineered mutation

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.