8TEA

HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Envelope protein UL128	polymer	163	18940.9	1	UniProt (Q38LY2) Pfam (PF25700) UniProt (by SIFTS) (P16837)	Human betaherpesvirus 5	UL128
2	B (D)	Envelope glycoprotein UL130	polymer	208	24018.3	1	UniProt (A0A0G2TB82) Pfam (PF11668) UniProt (by SIFTS) (P16772)	Human betaherpesvirus 5	ORFL272C_UL130,UL130 protein
3	C (E)	UL131A	polymer	130	15262.1	1	UniProt (Q38M12)	Human betaherpesvirus 5
4	D (G)	CS2pt1p2_A10L Fab light chain	polymer	216	22850.1	1		Homo sapiens (human)
5	E (H)	CS2pt1p2_A10L Fab heavy chain	polymer	243	25916.3	1		Homo sapiens (human)
6	F (F)	CS3pt1p4_C1L Fab heavy chain	polymer	223	23630.6	1		Homo sapiens (human)
7	G (I)	CS3pt1p4_C1L Fab light chain	polymer	218	23239.7	1		Homo sapiens (human)

Sequence modifications

C: 28 - 171 (UniProt: Q38LY2)

PDB	External Database	Details
Met 9	-	expression tag
Glu 10	-	expression tag
Trp 11	-	expression tag
Ser 12	-	expression tag
Trp 13	-	expression tag
Val 14	-	expression tag
Phe 15	-	expression tag
Leu 16	-	expression tag
Phe 17	-	expression tag
Phe 18	-	expression tag
Leu 19	-	expression tag
Ser 20	-	expression tag
Val 21	-	expression tag
Thr 22	-	expression tag
Thr 23	-	expression tag
Gly 24	-	expression tag
Val 25	-	expression tag
His 26	-	expression tag
Ser 27	-	expression tag

D: 26 - 214 (UniProt: A0A0G2TB82)

PDB	External Database	Details
Met 7	-	initiating methionine
Glu 8	-	expression tag
Trp 9	-	expression tag
Ser 10	-	expression tag
Trp 11	-	expression tag
Val 12	-	expression tag
Phe 13	-	expression tag
Leu 14	-	expression tag
Phe 15	-	expression tag
Phe 16	-	expression tag
Leu 17	-	expression tag
Ser 18	-	expression tag
Val 19	-	expression tag
Thr 20	-	expression tag
Thr 21	-	expression tag
Gly 22	-	expression tag
Val 23	-	expression tag
His 24	-	expression tag
Ser 25	-	expression tag

E: 19 - 129 (UniProt: Q38M12)

PDB	External Database	Details
Met 0	-	expression tag
Glu 1	-	expression tag
Trp 2	-	expression tag
Ser 3	-	expression tag
Trp 4	-	expression tag
Val 5	-	expression tag
Phe 6	-	expression tag
Leu 7	-	expression tag
Phe 8	-	expression tag
Phe 9	-	expression tag
Leu 10	-	expression tag
Ser 11	-	expression tag
Val 12	-	expression tag
Thr 13	-	expression tag
Thr 14	-	expression tag
Gly 15	-	expression tag
Val 16	-	expression tag
His 17	-	expression tag
Ser 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	153857.9
All*	Total formula weight	153857.9

*Water molecules are not included.