8TE6

Crystal structure of a multiple lysine-to-arginine substitution mutant of the human CRIg C3b-binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	V-set and immunoglobulin domain-containing protein 4	polymer	123	13973.6	1	UniProt (Q9Y279) Pfam (PF07686)	Homo sapiens (human)	Protein Z39Ig
2	B (A)	water	water		18.0	152	Chemie (HOH)

Sequence modifications

A: 1 - 118 (UniProt: Q9Y279)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Thr -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Arg 15	Lys 34	engineered mutation
Arg 36	Lys 55	engineered mutation
Arg 62	Lys 81	engineered mutation
Arg 72	Lys 91	engineered mutation
Arg 110	Lys 129	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13973.6
All*	Total formula weight	13973.6

*Water molecules are not included.