8TDD
Structure of PYCR1 complexed with NADH and 2-(furan-2-yl)acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Pyrroline-5-carboxylate reductase 1, mitochondrial | polymer | 316 | 33532.6 | 5 | UniProt (P32322) Pfam (PF03807) Pfam (PF14748) | Homo sapiens (human) | P5C reductase 1,P5CR 1 |
| 2 | F, H, K, N, P (A, B, C, D, E) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 5 | Chemie (NAI) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (928) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (11250888) PubChem (129607000) PubChem (129628338) PubChem (12309341) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 3 | G, J, M, O (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | I, L (B, C) | (furan-2-yl)acetic acid | non-polymer | 126.1 | 2 | Chemie (SJU) PubChem (75974) | |||
| 5 | Q, R, S, T, U (A, B, C, D, E) | water | water | 18.0 | 712 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 294 (UniProt: P32322)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | initiating methionine |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 167662.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3963.7 | |
| All* | Total formula weight | 171626.5 |
