8TD1
Structure of PYCR1 complexed with 3-(6-Oxa-9-azaspiro(4.5)decane-9-carbonyl)benzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Pyrroline-5-carboxylate reductase 1, mitochondrial | polymer | 316 | 33532.6 | 5 | UniProt (P32322) Pfam (PF03807) Pfam (PF14748) In PDB | Homo sapiens (human) | P5C reductase 1,P5CR 1 |
| 2 | A, B, C, D, E | 3-(6-oxa-9-azaspiro[4.5]decane-9-carbonyl)benzoic acid | non-polymer | 289.3 | 5 | Chemie (ZRZ) | |||
| 3 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | B, C, D, E | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 425 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 0 - 294 (UniProt: P32322)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | initiating methionine |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 167662.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1937.0 | |
| All* | Total formula weight | 169599.9 |
